Comparative Characterization of MicroRNAs from the Liver Flukes Fasciola gigantica and F. hepatica

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Comparative Characterization of MicroRNAs from the Liver Flukes Fasciola gigantica and F. hepatica

MicroRNAs (miRNAs) are key regulators of gene expression at the post-transcription level. The present study specifically explored and compared the miRNA expression profiles of F. gigantica and F. hepatica using an integrated sequencing and bioinformatics platform and quantitative real-time PCR. Nineteen and 16 miRNA candidates were identified from F. gigantica and F. hepatica, respectively. The...

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Bioaccumulation of Some Heavy Metals in the Liver Flukes Fasciola hepatica and F. gigantica

BACKGROUND Heavy metals tend to bioaccumulate in living organisms, and their accumulation has been a major concern. As mammals are known to excrete heavy metals via their bile, it seems to be very promising to analyse metal burdens of parasites that infect the biliary tree such as liver flukes of the genus Fasciola. The present study was carried out to evaluate F. hepatica and F. gigantica as b...

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bioaccumulation of some heavy metals in the liver flukes fasciola hepatica and f. gigantica.

background: heavy metals tend to bioaccumulate in living organisms, and their accumulation has been a major concern. as mammals are known to excrete heavy metals via their bile, it seems to be very promising to analyse metal burdens of par-asites that infect the biliary tree such as liver flukes of the genus fasciola . the pre-sent study was carried out to evaluate f. hepatica and f. gigantica ...

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Determination of somatic and excretory-secretory antigens of Fasciola hepatica and Fasciola gigantica using SDS-PAGE

Human fascioliasis due to unknown species and animal fascioliasis caused by both or one of Fasciola spp. are commonly seen in Iran. To compare electrophoretic patterns of somatic and excretory-secretory antigens of F. hepatica and F. gigantica  by sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE), the adult flukes were collected from infected slaughtered bovine livers. E/S a...

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Comparative Evaluation of in Vitro effects of Praziquantel (PZQ) on the Enzyme Activities of the Excretory - Secretory Products (ESP) of Fasciola hepatica and F. gigantica Parasites

Excretory-secretory products (ESP) play an important role in the host biochemical defense by means of activities of detoxifying and antioxidant enzymes. The aim of this study was to evaluate praziquantel (PZQ) effects by detection of glutathione S- transferase (GST) and superoxide dismutase (SOD) enzymes activities in ESP samples of Fasciola spp. Fasciola gigantica and Fasciola hepatica a...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2012

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0053387